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Site-specific C-terminal dinitrophenylation to reconstitute the antibody Fc functions for nanobodies
Nanobodies are a class of camelid-derived single-domain antibodies that have many potential advantages over conventional antibodies and have been utilized to develop new therapeutic strategies for cancer and other diseases. However, nanobodies lack the Fc region of a conventional antibody, which pos...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006623/ https://www.ncbi.nlm.nih.gov/pubmed/32110296 http://dx.doi.org/10.1039/c9sc03840j |