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Site-specific C-terminal dinitrophenylation to reconstitute the antibody Fc functions for nanobodies

Nanobodies are a class of camelid-derived single-domain antibodies that have many potential advantages over conventional antibodies and have been utilized to develop new therapeutic strategies for cancer and other diseases. However, nanobodies lack the Fc region of a conventional antibody, which pos...

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Detalles Bibliográficos
Autores principales: Hong, Haofei, Zhou, Zhifang, Zhou, Kun, Liu, Shaozhong, Guo, Zhongwu, Wu, Zhimeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006623/
https://www.ncbi.nlm.nih.gov/pubmed/32110296
http://dx.doi.org/10.1039/c9sc03840j