Design, synthesis and α-glucosidase inhibition study of novel embelin derivatives

Embelin is a naturally occurring para-benzoquinone isolated from Embelia ribes (Burm. f.) of the Myrsinaceae family. It was first discovered to have potent inhibitory activity (IC(50) = 4.2 μM) against α-glucosidase in this study. Then, four series of novel embelin derivatives were designed, prepare...

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Detalles Bibliográficos
Autores principales: Chen, Xiaole, Gao, Min, Jian, Rongchao, Hong, Weiqian David, Tang, Xiaowen, Li, Yuling, Zhao, Denggao, Zhang, Kun, Chen, Wenhua, Zheng, Xi, Sheng, Zhaojun, Wu, Panpan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006637/
https://www.ncbi.nlm.nih.gov/pubmed/31969031
http://dx.doi.org/10.1080/14756366.2020.1715386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006637/
https://www.ncbi.nlm.nih.gov/pubmed/31969031
http://dx.doi.org/10.1080/14756366.2020.1715386

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