A class of carbonic anhydrase IX/XII – selective carboxylate inhibitors

A small series of 2,4-dioxothiazolidinyl acetic acids was prepared from thiourea, chloroacetic acid, aromatic aldehydes, and ethyl-2-bromoacetate. They were assayed for the inhibition of four physiologically relevant carbonic anhydrase (CA, EC 4.2.1.1) isoforms of human (h) origin, the cytosolic hCA...

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Detalles Bibliográficos
Autores principales: Alhameed, Rakia Abd, Berrino, Emanuela, Almarhoon, Zainab, El-Faham, Ayman, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006686/
https://www.ncbi.nlm.nih.gov/pubmed/31967484
http://dx.doi.org/10.1080/14756366.2020.1715388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006686/
https://www.ncbi.nlm.nih.gov/pubmed/31967484
http://dx.doi.org/10.1080/14756366.2020.1715388

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