Metformin Activates the AMPK-mTOR Pathway by Modulating lncRNA TUG1 to Induce Autophagy and Inhibit Atherosclerosis

BACKGROUND: Metformin has been shown to inhibit the proliferation and migration of vascular wall cells. However, the mechanism through which metformin acts on atherosclerosis (AS) via the long non-coding RNA taurine up-regulated gene 1 (lncRNA TUG1) is still unknown. Thus, this research investigated...

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Detalles Bibliográficos
Autores principales: You, Ganhua, Long, Xiangshu, Song, Fang, Huang, Jing, Tian, Maobo, Xiao, Yan, Deng, Shiyan, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006854/
https://www.ncbi.nlm.nih.gov/pubmed/32099330
http://dx.doi.org/10.2147/DDDT.S233932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006854/
https://www.ncbi.nlm.nih.gov/pubmed/32099330
http://dx.doi.org/10.2147/DDDT.S233932

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