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Differential Effects of Ticagrelor With or Without Aspirin on Platelet Reactivity and Coagulation Activation: A Randomized Trial in Healthy Volunteers

Dual antiplatelet therapy (DAPT) is standard in acute coronary heart disease but confers a bleeding risk. To compare the effects of ticagrelor‐monotherapy with ticagrelor‐based DAPT on hemostatic system activation, we conducted a randomized controlled trial in 44 volunteers using a loading‐dose regi...

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Detalles Bibliográficos
Autores principales: Traby, Ludwig, Kollars, Marietta, Kaider, Alexandra, Siller‐Matula, Jolanta M., Wolkersdorfer, Martin F., Wolzt, Michael, Kyrle, Paul A., Eichinger, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006887/
https://www.ncbi.nlm.nih.gov/pubmed/31442298
http://dx.doi.org/10.1002/cpt.1616