The dipeptidyl peptidase-4 inhibitor, linagliptin, improves cognitive impairment in streptozotocin-induced diabetic mice by inhibiting oxidative stress and microglial activation

OBJECTIVE: Accumulating epidemiological studies have demonstrated that diabetes is an important risk factor for dementia. However, the underlying pathological and molecular mechanisms, and effective treatment, have not been fully elucidated. Herein, we investigated the effect of the dipeptidyl pepti...

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Detalles Bibliográficos
Autores principales: Ide, Makoto, Sonoda, Noriyuki, Inoue, Tomoaki, Kimura, Shinichiro, Minami, Yohei, Makimura, Hiroaki, Hayashida, Eiichi, Hyodo, Fuminori, Yamato, Mayumi, Takayanagi, Ryoichi, Inoguchi, Toyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006898/
https://www.ncbi.nlm.nih.gov/pubmed/32032367
http://dx.doi.org/10.1371/journal.pone.0228750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006898/
https://www.ncbi.nlm.nih.gov/pubmed/32032367
http://dx.doi.org/10.1371/journal.pone.0228750

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