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The C(2)A domain of synaptotagmin is an essential component of the calcium sensor for synaptic transmission
The synaptic vesicle protein, synaptotagmin, is the principle Ca(2+) sensor for synaptic transmission. Ca(2+) influx into active nerve terminals is translated into neurotransmitter release by Ca(2+) binding to synaptotagmin’s tandem C2 domains, triggering the fast, synchronous fusion of multiple syn...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006929/ https://www.ncbi.nlm.nih.gov/pubmed/32032373 http://dx.doi.org/10.1371/journal.pone.0228348 |