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Affinity of rhodopsin to raft enables the aligned oligomer formation from dimers: Coarse-grained molecular dynamics simulation of disk membranes

The visual photopigment protein rhodopsin (Rh) is a typical G protein-coupled receptor (GPCR) that initiates the phototransduction cascade in retinal disk membrane of rod-photoreceptor cells. Rh molecule has a tendency to form dimer, and the dimer tends to form rows, which is suggested to heighten p...

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Detalles Bibliográficos
Autores principales: Kaneshige, Yukito, Hayashi, Fumio, Morigaki, Kenichi, Tanimoto, Yasushi, Yamashita, Hayato, Fujii, Masashi, Awazu, Akinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006936/
https://www.ncbi.nlm.nih.gov/pubmed/32032370
http://dx.doi.org/10.1371/journal.pone.0226123