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Direct Mass Spectrometry Analysis of Protein Complexes and Intact Proteins up to >70 kDa from Tissue

[Image: see text] Native liquid extraction surface analysis (LESA) mass spectrometry allows direct analysis of folded proteins and protein complexes from biological substrates, such as dried blood spots and thin tissue sections, by use of native-like extraction/ionization solvents. Previously, we ha...

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Detalles Bibliográficos
Autores principales: Griffiths, Rian L., Konijnenberg, Albert, Viner, Rosa, Cooper, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7006965/
https://www.ncbi.nlm.nih.gov/pubmed/31062957
http://dx.doi.org/10.1021/acs.analchem.9b00971