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Self-Assembly, Tunable Hydrogel Properties, and Selective Anti-Cancer Activity of a Carnosine-Derived Lipidated Peptide

[Image: see text] A novel lipopeptide C(16)KTTβAH was designed that incorporates the KTT tripeptide sequence from “Matrixyl” lipopeptides along with the bioactive βAH (β-alanine-histidine) carnosine dipeptide motif, attached to a C(16) hexadecyl lipid chain. We show that this peptide amphiphile self...

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Detalles Bibliográficos
Autores principales: Castelletto, Valeria, Edwards-Gayle, Charlotte J. C., Greco, Francesca, Hamley, Ian W., Seitsonen, Jani, Ruokolainen, Janne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007010/
https://www.ncbi.nlm.nih.gov/pubmed/31407889
http://dx.doi.org/10.1021/acsami.9b09065