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Understanding Ligand Binding Selectivity in a Prototypical GPCR Family
[Image: see text] Adenosine receptors are involved in many pathological conditions and are thus promising drug targets. However, developing drugs that target this GPCR subfamily is a challenging task. A number of drug candidates fail due to lack of selectivity which results in unwanted side effects....
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007187/ https://www.ncbi.nlm.nih.gov/pubmed/31125224 http://dx.doi.org/10.1021/acs.jcim.9b00298 |