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CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility

Synaptodendritic pruning is a common cause of cognitive decline in neurological disorders, including HIV-associated neurocognitive disorders (HAND). HAND persists in treated patients as a result of chronic inflammation and low-level expression of viral proteins, though the mechanisms involved in syn...

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Detalles Bibliográficos
Autores principales: Festa, Lindsay K, Irollo, Elena, Platt, Brian J, Tian, Yuzen, Floresco, Stan, Meucci, Olimpia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007222/
https://www.ncbi.nlm.nih.gov/pubmed/31971513
http://dx.doi.org/10.7554/eLife.49717