Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins

RNA granules are protein/RNA condensates. How specific mRNAs are recruited to cytoplasmic RNA granules is not known. Here, we characterize the transcriptome and assembly of P granules, RNA granules in the C. elegans germ plasm. We find that P granules recruit mRNAs by condensation with the disordere...

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Detalles Bibliográficos
Autores principales: Lee, Chih-Yung S, Putnam, Andrea, Lu, Tu, He, ShuaiXin, Ouyang, John Paul T, Seydoux, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007223/
https://www.ncbi.nlm.nih.gov/pubmed/31975687
http://dx.doi.org/10.7554/eLife.52896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007223/
https://www.ncbi.nlm.nih.gov/pubmed/31975687
http://dx.doi.org/10.7554/eLife.52896

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