Uncovering the Early Stages of Domain Melting in Calmodulin with Ultrafast Temperature-Jump Infrared Spectroscopy

[Image: see text] The signaling protein calmodulin (CaM) undergoes a well-known change in secondary structure upon binding Ca(2+), but the structural plasticity of the Ca(2+)-free apo state is linked to CaM functionality. Variable temperature studies of apo-CaM indicate two structural transitions at...

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Detalles Bibliográficos
Autores principales: Minnes, Lucy, Greetham, Gregory M., Shaw, Daniel J., Clark, Ian P., Fritzsch, Robby, Towrie, Michael, Parker, Anthony W., Henry, Alistair J., Taylor, Richard J., Hunt, Neil T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007250/
https://www.ncbi.nlm.nih.gov/pubmed/31557034
http://dx.doi.org/10.1021/acs.jpcb.9b08870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007250/
https://www.ncbi.nlm.nih.gov/pubmed/31557034
http://dx.doi.org/10.1021/acs.jpcb.9b08870

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