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Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms
Secondary drug resistance stems from dynamic clonal evolution during the development of a prior primary resistance. This collateral type of resistance is often a characteristic of cancer recurrence. Yet, mechanisms that drive this collateral resistance and their drug-specific trajectories are still...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007258/ https://www.ncbi.nlm.nih.gov/pubmed/32083171 http://dx.doi.org/10.1126/sciadv.aav7416 |