Cargando…
Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms
Secondary drug resistance stems from dynamic clonal evolution during the development of a prior primary resistance. This collateral type of resistance is often a characteristic of cancer recurrence. Yet, mechanisms that drive this collateral resistance and their drug-specific trajectories are still...
Autores principales: | Aldonza, Mark Borris D., Ku, Jayoung, Hong, Ji-Young, Kim, Donghwa, Yu, Seung Jung, Lee, Min-Seok, Prayogo, Monica Celine, Tan, Stephanie, Kim, Dayeon, Han, Jinju, Lee, Sang Kook, Im, Sung Gap, Ryu, Han Suk, Kim, Yoosik |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007258/ https://www.ncbi.nlm.nih.gov/pubmed/32083171 http://dx.doi.org/10.1126/sciadv.aav7416 |
Ejemplares similares
-
Chemotherapy confers a conserved secondary tolerance to EGFR inhibition via AXL-mediated signaling bypass
por: Aldonza, Mark Borris D., et al.
Publicado: (2021) -
Multiplicity of acquired cross-resistance in paclitaxel-resistant cancer cells is associated with feedback control of TUBB3 via FOXO3a-mediated ABCB1 regulation
por: Aldonza, Mark Borris D., et al.
Publicado: (2016) -
Dual Targeting of EGFR with PLK1 Exerts Therapeutic Synergism in Taxane-Resistant Lung Adenocarcinoma by Suppressing ABC Transporters
por: Shin, Sol-Bi, et al.
Publicado: (2021) -
Paclitaxel-resistant cancer cell-derived secretomes elicit ABCB1-associated docetaxel cross-resistance and escape from apoptosis through FOXO3a-driven glycolytic regulation
por: Aldonza, Mark Borris D, et al.
Publicado: (2017) -
Resveratrol Attenuates the Mitochondrial RNA-Mediated Cellular Response to Immunogenic Stress
por: Yoon, Jimin, et al.
Publicado: (2023)