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Phosphoregulation of Rad51/Rad52 by CDK1 functions as a molecular switch for cell cycle–specific activation of homologous recombination

Homologous recombination is exquisitely activated only during specific cell phases. In the G(1) phase, homologous recombination activity is completely suppressed. According to previous reports, the activation of homologous recombination during specific cell phases depends on the kinase activity of c...

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Detalles Bibliográficos
Autores principales: Lim, Gyubum, Chang, Yeonji, Huh, Won-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007264/
https://www.ncbi.nlm.nih.gov/pubmed/32083180
http://dx.doi.org/10.1126/sciadv.aay2669