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Phosphoregulation of Rad51/Rad52 by CDK1 functions as a molecular switch for cell cycle–specific activation of homologous recombination
Homologous recombination is exquisitely activated only during specific cell phases. In the G(1) phase, homologous recombination activity is completely suppressed. According to previous reports, the activation of homologous recombination during specific cell phases depends on the kinase activity of c...
Autores principales: | Lim, Gyubum, Chang, Yeonji, Huh, Won-Ki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007264/ https://www.ncbi.nlm.nih.gov/pubmed/32083180 http://dx.doi.org/10.1126/sciadv.aay2669 |
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