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Rapid transport of germ-mimetic nanoparticles with dual conformational polyethylene glycol chains in biological tissues

Polyethylene glycols (PEGs) can improve the diffusivity of nanoparticles (NPs) in biological hydrogels, while extended PEG chains severely impede cellular uptake of NPs. Inspired by invasive germs with flagellum-driven mucus-penetrating and fimbriae-mediated epithelium-adhering abilities, we develop...

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Detalles Bibliográficos
Autores principales: Yang, Yiwei, Tian, Falin, Nie, Di, Liu, Yuan, Qian, Kun, Yu, Miaorong, Wang, Aohua, Zhang, Yaqi, Shi, Xinghua, Gan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007268/
https://www.ncbi.nlm.nih.gov/pubmed/32083187
http://dx.doi.org/10.1126/sciadv.aay9937