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Rapid transport of germ-mimetic nanoparticles with dual conformational polyethylene glycol chains in biological tissues
Polyethylene glycols (PEGs) can improve the diffusivity of nanoparticles (NPs) in biological hydrogels, while extended PEG chains severely impede cellular uptake of NPs. Inspired by invasive germs with flagellum-driven mucus-penetrating and fimbriae-mediated epithelium-adhering abilities, we develop...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007268/ https://www.ncbi.nlm.nih.gov/pubmed/32083187 http://dx.doi.org/10.1126/sciadv.aay9937 |