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Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

[Image: see text] Many oral mucosal conditions cause considerable and prolonged pain that to date has been difficult to alleviate via topical delivery, and the use of injection causes many patients dental anxiety and needle-prick pain. Therefore, developing a noninjectable drug delivery system as an...

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Detalles Bibliográficos
Autores principales: Clitherow, Katharina H., Murdoch, Craig, Spain, Sebastian Guy, Handler, Anna Mette, Colley, Helen E., Stie, Mai Bay, Mørck Nielsen, Hanne, Janfelt, Christian, Hatton, Paul V., Jacobsen, Jette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007276/
https://www.ncbi.nlm.nih.gov/pubmed/31361498
http://dx.doi.org/10.1021/acs.molpharmaceut.9b00535