Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease

The pre-metastatic niche (PMN) represents an abnormal microenvironment devoid of cancer cells, but favoring tumor growth. Little is known about the mechanisms that generate the PMN or their effects on host cells within metastasis-prone organs. Here, we investigated by using spontaneous metastatic mo...

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Detalles Bibliográficos
Autores principales: Charan, Manish, Dravid, Piyush, Cam, Maren, Setty, Bhuvana, Roberts, Ryan D., Houghton, Peter J., Cam, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007290/
https://www.ncbi.nlm.nih.gov/pubmed/32082485
http://dx.doi.org/10.18632/oncotarget.27433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007290/
https://www.ncbi.nlm.nih.gov/pubmed/32082485
http://dx.doi.org/10.18632/oncotarget.27433

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