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Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo

Aberrant ocular angiogenesis can underpin vision loss in leading causes of blindness, including neovascular age-related macular degeneration and proliferative diabetic retinopathy. Current pharmacological interventions require repeated invasive administrations, may lack efficacy and are associated w...

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Detalles Bibliográficos
Autores principales: Merrigan, Stephanie L., Park, Bomina, Ali, Zaheer, Jensen, Lasse D., Corson, Timothy W., Kennedy, Breandán N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007294/
https://www.ncbi.nlm.nih.gov/pubmed/32082484
http://dx.doi.org/10.18632/oncotarget.27380