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PREX1 drives spontaneous bone dissemination of ER+ breast cancer cells
A significant proportion of breast cancer patients develop bone metastases, but the mechanisms regulating tumor cell dissemination from the primary site to the skeleton remain largely unknown. Using a novel model of spontaneous bone metastasis derived from human ER+ MCF7 cells, molecular profiling r...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007387/ https://www.ncbi.nlm.nih.gov/pubmed/31636389 http://dx.doi.org/10.1038/s41388-019-1064-3 |