Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia

By comparing imatinib-sensitive and -resistant chronic myeloid leukemia (CML) cell models, we investigated the molecular mechanisms by which tetrahydrobenzimidazole derivative TMQ0153 triggered caspase-dependent apoptosis at low concentrations accompanied by loss of mitochondrial membrane potential...

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Detalles Bibliográficos
Autores principales: Song, Sungmi, Lee, Jin-Young, Ermolenko, Ludmila, Mazumder, Aloran, Ji, Seungwon, Ryu, Heeju, Kim, HyeJin, Kim, Dong-Wook, Lee, Jung Weon, Dicato, Mario, Christov, Christo, Schnekenburger, Michael, Cerella, Claudia, Gérard, Déborah, Orlikova-Boyer, Barbora, Al-Mourabit, Ali, Diederich, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007439/
https://www.ncbi.nlm.nih.gov/pubmed/32034134
http://dx.doi.org/10.1038/s41419-020-2304-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007439/
https://www.ncbi.nlm.nih.gov/pubmed/32034134
http://dx.doi.org/10.1038/s41419-020-2304-8

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