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Time-dependent effects of histone deacetylase inhibition in sepsis-associated acute kidney injury

BACKGROUND: Sepsis, a dysregulated host response to infection with results in organ dysfunction, has been a major challenge to the development of effective therapeutics. Sepsis-associated acute kidney injury (S-AKI) results in a 3–5-fold increase in the risk of hospital mortality compared to sepsis...

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Detalles Bibliográficos
Autores principales: Wen, Xiaoyan, Li, Shengnan, Frank, Alicia, Chen, Xiukai, Emlet, David, Hukriede, Neil A., Kellum, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007462/
https://www.ncbi.nlm.nih.gov/pubmed/32034542
http://dx.doi.org/10.1186/s40635-020-0297-3