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Time-dependent effects of histone deacetylase inhibition in sepsis-associated acute kidney injury
BACKGROUND: Sepsis, a dysregulated host response to infection with results in organ dysfunction, has been a major challenge to the development of effective therapeutics. Sepsis-associated acute kidney injury (S-AKI) results in a 3–5-fold increase in the risk of hospital mortality compared to sepsis...
Autores principales: | Wen, Xiaoyan, Li, Shengnan, Frank, Alicia, Chen, Xiukai, Emlet, David, Hukriede, Neil A., Kellum, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007462/ https://www.ncbi.nlm.nih.gov/pubmed/32034542 http://dx.doi.org/10.1186/s40635-020-0297-3 |
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