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Arrhythmogenic late Ca(2+) sparks in failing heart cells and their control by action potential configuration
Sudden death in heart failure patients is a major clinical problem worldwide, but it is unclear how arrhythmogenic early afterdepolarizations (EADs) are triggered in failing heart cells. To examine EAD initiation, high-sensitivity intracellular Ca(2+) measurements were combined with action potential...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007549/ https://www.ncbi.nlm.nih.gov/pubmed/31969455 http://dx.doi.org/10.1073/pnas.1918649117 |