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Pressure sensing through Piezo channels controls whether cells migrate with blebs or pseudopods
Blebs and pseudopods can both power cell migration, with blebs often favored in tissues, where cells encounter increased mechanical resistance. To investigate how migrating cells detect and respond to mechanical forces, we used a “cell squasher” to apply uniaxial pressure to Dictyostelium cells chem...
Autores principales: | Srivastava, Nishit, Traynor, David, Piel, Matthieu, Kabla, Alexandre J., Kay, Robert R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007555/ https://www.ncbi.nlm.nih.gov/pubmed/31964823 http://dx.doi.org/10.1073/pnas.1905730117 |
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