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Characterising a human endogenous retrovirus(HERV)-derived tumour-associated antigen: enriched RNA-Seq analysis of HERV-K(HML-2) in mantle cell lymphoma cell lines

BACKGROUND: The cell-surface attachment protein (Env) of the HERV-K(HML-2) lineage of endogenous retroviruses is a potentially attractive tumour-associated antigen for anti-cancer immunotherapy. The human genome contains around 100 integrated copies (called proviruses or loci) of the HERV-K(HML-2) v...

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Detalles Bibliográficos
Autores principales: Tatkiewicz, Witold, Dickie, James, Bedford, Franchesca, Jones, Alexander, Atkin, Mark, Kiernan, Michele, Maze, Emmanuel Atangana, Agit, Bora, Farnham, Garry, Kanapin, Alexander, Belshaw, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007669/
https://www.ncbi.nlm.nih.gov/pubmed/32055257
http://dx.doi.org/10.1186/s13100-020-0204-1