Thalamostriatal degeneration contributes to dystonia and cholinergic interneuron dysfunction in a mouse model of Huntington’s disease

Huntington’s disease (HD) is an autosomal dominant trinucleotide repeat disorder characterized by choreiform movements, dystonia and striatal neuronal loss. Amongst multiple cellular processes, abnormal neurotransmitter signalling and decreased trophic support from glutamatergic cortical afferents a...

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Detalles Bibliográficos
Autores principales: Crevier-Sorbo, Gabriel, Rymar, Vladimir V., Crevier-Sorbo, Raphael, Sadikot, Abbas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007676/
https://www.ncbi.nlm.nih.gov/pubmed/32033588
http://dx.doi.org/10.1186/s40478-020-0878-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007676/
https://www.ncbi.nlm.nih.gov/pubmed/32033588
http://dx.doi.org/10.1186/s40478-020-0878-0

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