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Prenylflavonoid Icariin Induces Estrogen Response Element–Independent Estrogenic Responses in a Tissue-Selective Manner

Icariin, a flavonoid phytoestrogen derived from Herba epimedii, has been reported to exert estrogenic effects in bone and activate phosphorylation of estrogen receptor (ER) α in osteoblastic cells. However, it is unclear whether icariin selectively exerts estrogenic activities in bone without induci...

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Detalles Bibliográficos
Autores principales: Zhou, Liping, Poon, Christina Chui-Wa, Wong, Ka-Ying, Cao, Sisi, Yu, Wenxuan, Dong, Xiaoli, Lee, Wayne Yuk-Wai, Zhang, Yan, Wong, Man-Sau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007805/
https://www.ncbi.nlm.nih.gov/pubmed/32051921
http://dx.doi.org/10.1210/jendso/bvz025