Cargando…

Prenylflavonoid Icariin Induces Estrogen Response Element–Independent Estrogenic Responses in a Tissue-Selective Manner

Icariin, a flavonoid phytoestrogen derived from Herba epimedii, has been reported to exert estrogenic effects in bone and activate phosphorylation of estrogen receptor (ER) α in osteoblastic cells. However, it is unclear whether icariin selectively exerts estrogenic activities in bone without induci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Liping, Poon, Christina Chui-Wa, Wong, Ka-Ying, Cao, Sisi, Yu, Wenxuan, Dong, Xiaoli, Lee, Wayne Yuk-Wai, Zhang, Yan, Wong, Man-Sau
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007805/ https://www.ncbi.nlm.nih.gov/pubmed/32051921 http://dx.doi.org/10.1210/jendso/bvz025

Ejemplares similares

Water Extract of Rhizoma Drynaria Selectively Exerts Estrogenic Activities in Ovariectomized Rats and Estrogen Receptor-Positive Cells
por: Zhou, Liping, et al.
Publicado: (2022)

Selective Estrogen Receptor Modulator-Like Activities of Herba epimedii Extract and its Interactions With Tamoxifen and Raloxifene in Bone Cells and Tissues
por: Zhou, Liping, et al.
Publicado: (2021)

Icariin Treatment Enhanced the Skeletal Response to Exercise in Estrogen-Deficient Rats
por: Zhao, Renqing, et al.
Publicado: (2019)

Oleanolic Acid Modulates 25-Hydroxyvitamin D(3) 1-alpha-hydroxylase in Osteoblasts and Human Mesenchymal Stem Cells
por: Yu, Wen-Xuan, et al.
Publicado: (2021)

Interactions of dietary estrogens with human estrogen receptors and the effect on estrogen receptor-estrogen response element complex formation.
por: Nikov, G N, et al.
Publicado: (2000)

The Antioxidant Activity of Prenylflavonoids
por: Santos, Clementina M. M., et al.
Publicado: (2020)

Icariin Exerts Estrogen-Like Actions on Proliferation of Osteoblasts in Vitro via Membrane Estrogen Receptors-Mediated Non-nuclear Effects
por: Zhang, Dapeng, et al.
Publicado: (2022)

Antioxidant activities of licorice-derived prenylflavonoids
por: Kim, Hyo Jung, et al.
Publicado: (2012)

Icariin, but Not Genistein, Exerts Osteogenic and Anti-apoptotic Effects in Osteoblastic Cells by Selective Activation of Non-genomic ERα Signaling
por: Ho, Ming-Xian, et al.
Publicado: (2018)

Identification of Estrogen Response Element in Aquaporin-3 Gene that Mediates Estrogen-induced Cell Migration and Invasion in Estrogen Receptor-positive Breast Cancer
por: Huang, Yi-Ting, et al.
Publicado: (2015)

Two Estrogen Response Element Sequences Near the PCNA Gene Are Not Responsible for Its Estrogen-Enhanced Expression in MCF7 Cells
por: Wang, Cheng, et al.
Publicado: (2008)

Role of Estrogen Response Element in the Human Prolactin Gene: Transcriptional Response and Timing
por: McNamara, Anne V., et al.
Publicado: (2016)

Estrogen stimulates SREBP2 expression in hepatic cell lines via an estrogen response element in the SREBP2 promoter
por: Meng, Ye, et al.
Publicado: (2019)

Novel estrogen-responsive genes (ERGs) for the evaluation of estrogenic activity
por: Nishi, Kentaro, et al.
Publicado: (2022)

AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner
por: Jian, Lei, et al.
Publicado: (2020)

A tale of two estrogen receptors (ERs): how differential ER-estrogen responsive element interactions contribute to subtype-specific transcriptional responses
por: Huang, Jing, et al.
Publicado: (2006)

In silico selection of an aptamer to estrogen receptor alpha using computational docking employing estrogen response elements as aptamer-alike molecules
por: Ahirwar, Rajesh, et al.
Publicado: (2016)

Estradiol-Estrogen Receptor α Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway
por: Yaşar, Pelin, et al.
Publicado: (2016)

Estrogen Induces Selective Transcription of Caveolin1 Variants in Human Breast Cancer through Estrogen Responsive Element-Dependent Mechanisms
por: Romano, Antonella, et al.
Publicado: (2020)

HER2 and ERβ2 downregulate estrogen-responsive element-mediated transcription activity of ERα-positive cells in response to estrogen stimulation
por: Park, B-W, et al.
Publicado: (2005)

The role of mesenchymal estrogen receptor 1 in mouse uterus in response to estrogen
por: Furuminato, Keita, et al.
Publicado: (2023)

Comparative Effects of Er-Xian Decoction, Epimedium Herbs, and Icariin with Estrogen on Bone and Reproductive Tissue in Ovariectomized Rats
por: Xue, Liming, et al.
Publicado: (2012)

Ginsenoside Rg1 activates ligand-independent estrogenic effects via rapid estrogen receptor signaling pathway
por: Gao, Quan-Gui, et al.
Publicado: (2019)

Melatonin decreases estrogen receptor binding to estrogen response elements sites on the OCT4 gene in human breast cancer stem cells
por: Lopes, Juliana, et al.
Publicado: (2016)

Effects and Mechanisms of Five Psoralea Prenylflavonoids on Aging-Related Diseases
por: Zhou, Yi-Ting, et al.
Publicado: (2020)

High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer
por: Traphagen, Nicole A., et al.
Publicado: (2021)

Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion
por: Qin, Sisi, et al.
Publicado: (2017)

Estrogen response in luminal breast cancer
por: Rangel, Leticia B. A., et al.
Publicado: (2013)

Bioinformatics Analysis of Estrogen-Responsive Genes
por: Handel, Adam E.
Publicado: (2015)

Discovery of estrogen receptor α target genes and response elements in breast tumor cells
por: Lin, Chin-Yo, et al.
Publicado: (2004)

Good Estrogen Bad Estrogen
por: Barrett, JR
Publicado: (2000)

Estrogen accelerates heart regeneration by promoting the inflammatory response in zebrafish
por: Xu, Shisan, et al.
Publicado: (2020)

ZNF423 modulates the AMP-activated protein kinase pathway and metformin response in a single nucleotide polymorphisms, estrogen and selective estrogen receptor modulator dependent fashion
por: Qin, Sisi, et al.
Publicado: (2021)

RhoB modifies estrogen responses in breast cancer cells by influencing expression of the estrogen receptor
por: Médale-Giamarchi, Claire, et al.
Publicado: (2013)

Triclosan Lacks (Anti-)Estrogenic Effects in Zebrafish Cells but Modulates Estrogen Response in Zebrafish Embryos
por: Serra, Hélène, et al.
Publicado: (2018)

Estrogens regulate early embryonic development of the olfactory sensory system via estrogen-responsive glia
por: Takesono, Aya, et al.
Publicado: (2022)

A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses
por: Clusan, Léa, et al.
Publicado: (2021)

Estrogen-related receptor β deficiency alters body composition and response to restraint stress
por: Byerly, Mardi S, et al.
Publicado: (2013)

Using a customized DNA microarray for expression profiling of the estrogen-responsive genes to evaluate estrogen activity among natural estrogens and industrial chemicals.
por: Terasaka, Shunichi, et al.
Publicado: (2004)

KBERG: KnowledgeBase for Estrogen Responsive Genes
por: Tang, Suisheng, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_gm2j6dvfr7c47d2l9m7qjgeagv