Clinical implications of intratumor heterogeneity: challenges and opportunities

In this review, we highlight the role of intratumoral heterogeneity, focusing on the clinical and biological ramifications this phenomenon poses. Intratumoral heterogeneity arises through complex genetic, epigenetic, and protein modifications that drive phenotypic selection in response to environmen...

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Detalles Bibliográficos
Autores principales: Ramón y Cajal, Santiago, Sesé, Marta, Capdevila, Claudia, Aasen, Trond, De Mattos-Arruda, Leticia, Diaz-Cano, Salvador J., Hernández-Losa, Javier, Castellví, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007907/
https://www.ncbi.nlm.nih.gov/pubmed/31970428
http://dx.doi.org/10.1007/s00109-020-01874-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007907/
https://www.ncbi.nlm.nih.gov/pubmed/31970428
http://dx.doi.org/10.1007/s00109-020-01874-2

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