Adaptation to chronic acidic extracellular pH elicits a sustained increase in lung cancer cell invasion and metastasis

Acidic extracellular pH (pH(e)) is an important microenvironment for cancer cells. This study assessed whether adaptation to acidic pH(e) enhances the metastatic phenotype of tumor cells. The low metastatic variant of Lewis lung carcinoma (LLCm1) cells were subjected to stepwise acidification, estab...

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Detalles Bibliográficos
Autores principales: Sutoo, Shusaku, Maeda, Toyonobu, Suzuki, Atsuko, Kato, Yasumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007909/
https://www.ncbi.nlm.nih.gov/pubmed/31489536
http://dx.doi.org/10.1007/s10585-019-09990-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007909/
https://www.ncbi.nlm.nih.gov/pubmed/31489536
http://dx.doi.org/10.1007/s10585-019-09990-1

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