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Applications of off-gas mass spectrometry in fed-batch mammalian cell culture

Off-gas analysis using a magnetic sector mass spectrometer was performed in mammalian cell cultures in the fed-batch mode at the 5 L bench and 50 L pilot scales. Factors affecting the MS gas traces were identified during the duration of the fed-batch cultures. Correlation between viable cell concent...

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Detalles Bibliográficos
Autores principales: Goh, Hai-Yuan, Sulu, Michael, Alosert, Haneen, Lewis, Graham L., Josland, Graham D., Merriman, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007916/
https://www.ncbi.nlm.nih.gov/pubmed/31709471
http://dx.doi.org/10.1007/s00449-019-02242-2