Sensitivity of Kupffer cells and liver sinusoidal endothelial cells to ricin toxin and ricin toxin–Ab complexes

Ricin toxin is a plant‐derived, ribosome‐inactivating protein that is rapidly cleared from circulation by Kupffer cells (KCs) and liver sinusoidal endothelial cells (LSECs)—with fatal consequences. Rather than being inactivated, ricin evades normal degradative pathways and kills both KCs and LSECs w...

Descripción completa

Detalles Bibliográficos
Autores principales: Mooney, Bridget, Torres‐Velez, Fernando J., Doering, Jennifer, Ehrbar, Dylan J., Mantis, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Host Defense & Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008010/
https://www.ncbi.nlm.nih.gov/pubmed/31313388
http://dx.doi.org/10.1002/JLB.4A0419-123R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008010/
https://www.ncbi.nlm.nih.gov/pubmed/31313388
http://dx.doi.org/10.1002/JLB.4A0419-123R

Ejemplares similares