Involvement of the TNF-α Pathway in TKI Resistance and Suggestion of TNFR1 as a Predictive Biomarker for TKI Responsiveness in Clear Cell Renal Cell Carcinoma

BACKGROUND: Mechanism and predictive biomarkers for tyrosine kinase inhibitor (TKI) resistance of advanced clear cell renal cell carcinoma (ccRCC) have not been fully evaluated. METHODS: We performed gene expression profiling on samples from an acquired TKI resistance cohort that consisted of 10 cas...

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Detalles Bibliográficos
Autores principales: Hwang, Hee Sang, Park, Yun-Yong, Shin, Su-Jin, Go, Heounjeong, Park, Ja-Min, Yoon, Sun Young, Lee, Jae-Lyun, Cho, Yong Mee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008069/
https://www.ncbi.nlm.nih.gov/pubmed/32030920
http://dx.doi.org/10.3346/jkms.2020.35.e31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008069/
https://www.ncbi.nlm.nih.gov/pubmed/32030920
http://dx.doi.org/10.3346/jkms.2020.35.e31

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