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A NAG-Guided Nano-Delivery System for Redox- and pH-Triggered Intracellularly Sequential Drug Release in Cancer Cells

AIM: Sequential treatment with paclitaxel (PTXL) and gemcitabine (GEM) is considered clinically beneficial for non-small-cell lung cancer. This study aimed to investigate the effectiveness of a nano-system capable of sequential release of PTXL and GEM within cancer cells. METHODS: PTXL-ss-poly(6-O-m...

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Detalles Bibliográficos
Autores principales: Liang, Yan, Zhang, Jing, Tian, Baocheng, Wu, Zimei, Svirskis, Darren, Han, Jingtian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008180/
https://www.ncbi.nlm.nih.gov/pubmed/32103941
http://dx.doi.org/10.2147/IJN.S226249