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Layer-by-layer pH-sensitive nanoparticles for drug delivery and controlled release with improved therapeutic efficacy in vivo

In this work, a pH-sensitive liposome–polymer nanoparticle (NP) composed of lipid, hyaluronic acid (HA) and poly(β-amino ester) (PBAE) was prepared using layer-by-layer (LbL) method for doxorubicin (DOX) targeted delivery and controlled release to enhance the cancer treatment efficacy. The NP with p...

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Detalles Bibliográficos
Autores principales: Men, Wanfu, Zhu, Peiyao, Dong, Siyuan, Liu, Wenke, Zhou, Kun, Bai, Yu, Liu, Xiangli, Gong, Shulei, Zhang, Shuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008239/
https://www.ncbi.nlm.nih.gov/pubmed/31924103
http://dx.doi.org/10.1080/10717544.2019.1709922