Hypoxia Induces Growth Differentiation Factor 15 to Promote the Metastasis of Colorectal Cancer via PERK-eIF2α Signaling

Hypoxia plays an essential role in orchestrating Epithelial-mesenchymal transition and promoting metastasis of colorectal cancer. However, the underlying mechanisms are still not well elucidated. Here, we present that hypoxic exposure causes endoplasmic reticulum stress and activates the unfolded pr...

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Detalles Bibliográficos
Autores principales: Zheng, Hongtu, Wu, Yuchen, Guo, Tianan, Liu, Fangqi, Xu, Ye, Cai, Sanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008299/
https://www.ncbi.nlm.nih.gov/pubmed/32076610
http://dx.doi.org/10.1155/2020/5958272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008299/
https://www.ncbi.nlm.nih.gov/pubmed/32076610
http://dx.doi.org/10.1155/2020/5958272

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