Identification of a distinct desensitisation gate in the ATP-gated P2X2 receptor

P2X receptors are trimeric ATP-gated ion channels. In response to ATP binding, conformational changes lead to opening of the channel and ion flow. Current flow can decline during continued ATP binding in a process called desensitisation. The rate and extent of desensitisation is affected by multiple...

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Detalles Bibliográficos
Autores principales: Stavrou, Anastasios, Evans, Richard J., Schmid, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008354/
https://www.ncbi.nlm.nih.gov/pubmed/31843194
http://dx.doi.org/10.1016/j.bbrc.2019.12.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008354/
https://www.ncbi.nlm.nih.gov/pubmed/31843194
http://dx.doi.org/10.1016/j.bbrc.2019.12.028

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