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Identification of a distinct desensitisation gate in the ATP-gated P2X2 receptor
P2X receptors are trimeric ATP-gated ion channels. In response to ATP binding, conformational changes lead to opening of the channel and ion flow. Current flow can decline during continued ATP binding in a process called desensitisation. The rate and extent of desensitisation is affected by multiple...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008354/ https://www.ncbi.nlm.nih.gov/pubmed/31843194 http://dx.doi.org/10.1016/j.bbrc.2019.12.028 |