A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation

Small-molecule inhibitors of translation are critical tools to study the molecular mechanisms of protein synthesis. In this study, we sought to characterize how QL47, a host-targeted, small-molecule antiviral agent, inhibits steady-state viral protein expression. We demonstrate that this small molec...

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Detalles Bibliográficos
Autores principales: de Wispelaere, Mélissanne, Carocci, Margot, Burri, Dominique J., Neidermyer, William J., Olson, Calla M., Roggenbach, Imme, Liang, Yanke, Wang, Jinhua, Whelan, Sean P. J., Gray, Nathanael S., Yang, Priscilla L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008383/
https://www.ncbi.nlm.nih.gov/pubmed/31914414
http://dx.doi.org/10.1074/jbc.RA119.011132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008383/
https://www.ncbi.nlm.nih.gov/pubmed/31914414
http://dx.doi.org/10.1074/jbc.RA119.011132

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