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A broad-spectrum antiviral molecule, QL47, selectively inhibits eukaryotic translation

Small-molecule inhibitors of translation are critical tools to study the molecular mechanisms of protein synthesis. In this study, we sought to characterize how QL47, a host-targeted, small-molecule antiviral agent, inhibits steady-state viral protein expression. We demonstrate that this small molec...

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Detalles Bibliográficos
Autores principales:	de Wispelaere, Mélissanne, Carocci, Margot, Burri, Dominique J., Neidermyer, William J., Olson, Calla M., Roggenbach, Imme, Liang, Yanke, Wang, Jinhua, Whelan, Sean P. J., Gray, Nathanael S., Yang, Priscilla L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Protein Synthesis and Degradation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008383/ https://www.ncbi.nlm.nih.gov/pubmed/31914414 http://dx.doi.org/10.1074/jbc.RA119.011132

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