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The rOX‐stars of inflammation: links between the inflammasome and mitochondrial meltdown

The nod‐like receptor protein 3 (NLRP3) inflammasome drives inflammation in response to mitochondrial dysfunction. As metabolic powerhouses with prokaryotic ancestry, mitochondria are a cache for danger‐associated molecular patterns and pathogen‐associated molecular pattern‐like molecules that elici...

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Detalles Bibliográficos
Autores principales: Holley, Caroline L, Schroder, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008497/
https://www.ncbi.nlm.nih.gov/pubmed/32055400
http://dx.doi.org/10.1002/cti2.1109