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CLEAR: coverage-based limiting-cell experiment analysis for RNA-seq

BACKGROUND: Direct cDNA preamplification protocols developed for single-cell RNA-seq have enabled transcriptome profiling of precious clinical samples and rare cell populations without the need for sample pooling or RNA extraction. We term the use of single-cell chemistries for sequencing low number...

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Detalles Bibliográficos
Autores principales: Walker, Logan A., Sovic, Michael G., Chiang, Chi-Ling, Hu, Eileen, Denninger, Jiyeon K., Chen, Xi, Kirby, Elizabeth D., Byrd, John C., Muthusamy, Natarajan, Bundschuh, Ralf, Yan, Pearlly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008572/
https://www.ncbi.nlm.nih.gov/pubmed/32039730
http://dx.doi.org/10.1186/s12967-020-02247-6