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Meta-Analysis of Genome-Wide Association and Gene Expression Studies Implicates Donor T Cell Function and Cytokine Pathways in Acute GvHD

Graft-vs.-host disease (GvHD) is a major complication after allogeneic hematopoietic stem cell transplantation that causes mortality and severe morbidity. Genetic disparities in human leukocyte antigens between the recipient and donor are known contributors to the risk of the disease. However, the o...

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Detalles Bibliográficos
Autores principales: Hyvärinen, Kati, Koskela, Satu, Niittyvuopio, Riitta, Nihtinen, Anne, Volin, Liisa, Salmenniemi, Urpu, Putkonen, Mervi, Buño, Ismael, Gallardo, David, Itälä-Remes, Maija, Partanen, Jukka, Ritari, Jarmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008714/
https://www.ncbi.nlm.nih.gov/pubmed/32117222
http://dx.doi.org/10.3389/fimmu.2020.00019