Energy stress-mediated AMPK activation inhibits ferroptosis

Energy stress depletes ATP and induces cell death. Here, we identify an unexpected inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation. We found that ferroptotic cell death and lipid peroxidation can be inhibited by treatments...

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Detalles Bibliográficos
Autores principales: Lee, Hyemin, Zandkarimi, Fereshteh, Zhang, Yilei, Meena, Jitendra Kumar, Kim, Jongchan, Zhuang, Li, Tyagi, Siddhartha, Ma, Li, Westbrook, Thomas F., Steinberg, Gregory R, Nakada, Daisuke, Stockwell, Brent R., Gan, Boyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008777/
https://www.ncbi.nlm.nih.gov/pubmed/32029897
http://dx.doi.org/10.1038/s41556-020-0461-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008777/
https://www.ncbi.nlm.nih.gov/pubmed/32029897
http://dx.doi.org/10.1038/s41556-020-0461-8

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