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Ets1 Controls the Development of B Cell Autoimmune Responses in a Cell-Intrinsic Manner

Ets1 is emerging as a key transcription factor that is required to prevent autoimmunity in mice and humans. Ets1 is expressed in both B and T cells, and mice lacking Ets1 are characterized by excess B and T cell activation, leading to enhanced formation of Ab-secreting cells and high titers of autoa...

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Detalles Bibliográficos
Autores principales: Sunshine, Alex, Goich, David, Stith, Alifa, Sortino, Katherine, Dalton, Justin, Metcalfe, Sarah, Svensson, Eric C., Garrett-Sinha, Lee Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008956/
https://www.ncbi.nlm.nih.gov/pubmed/31356162
http://dx.doi.org/10.4049/immunohorizons.1900033