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Ets1 Controls the Development of B Cell Autoimmune Responses in a Cell-Intrinsic Manner
Ets1 is emerging as a key transcription factor that is required to prevent autoimmunity in mice and humans. Ets1 is expressed in both B and T cells, and mice lacking Ets1 are characterized by excess B and T cell activation, leading to enhanced formation of Ab-secreting cells and high titers of autoa...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008956/ https://www.ncbi.nlm.nih.gov/pubmed/31356162 http://dx.doi.org/10.4049/immunohorizons.1900033 |