Cargando…

Ets1 Controls the Development of B Cell Autoimmune Responses in a Cell-Intrinsic Manner

Ets1 is emerging as a key transcription factor that is required to prevent autoimmunity in mice and humans. Ets1 is expressed in both B and T cells, and mice lacking Ets1 are characterized by excess B and T cell activation, leading to enhanced formation of Ab-secreting cells and high titers of autoa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sunshine, Alex, Goich, David, Stith, Alifa, Sortino, Katherine, Dalton, Justin, Metcalfe, Sarah, Svensson, Eric C., Garrett-Sinha, Lee Ann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008956/ https://www.ncbi.nlm.nih.gov/pubmed/31356162 http://dx.doi.org/10.4049/immunohorizons.1900033

Ejemplares similares

Ets1 and IL17RA cooperate to regulate autoimmune responses and skin immunity to Staphylococcus aureus
por: Battaglia, Michael, et al.
Publicado: (2023)

MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner
por: Demeyer, Annelies, et al.
Publicado: (2019)

Ets1 Induces Dysplastic Changes When Expressed in Terminally-Differentiating Squamous Epidermal Cells
por: Nagarajan, Priyadharsini, et al.
Publicado: (2009)

PTPN22 Acts in a Cell Intrinsic Manner to Restrict the Proliferation and Differentiation of T Cells Following Antibody Lymphodepletion
por: Knipper, Johanna A., et al.
Publicado: (2020)

Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1
por: Saelee, Prontip, et al.
Publicado: (2017)

CABLES1 Deficiency Impairs Quiescence and Stress Responses of Hematopoietic Stem Cells in Intrinsic and Extrinsic Manners
por: He, Liang, et al.
Publicado: (2019)

Dendritic cells loaded with FK506 kill T cells in an antigen-specific manner and prevent autoimmunity in vivo
por: Orange, Dana E, et al.
Publicado: (2013)

Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma
por: Gluck, Christian, et al.
Publicado: (2019)

CMPK2 is a host restriction factor that inhibits infection of multiple coronaviruses in a cell-intrinsic manner
por: Zhu, Mingjun, et al.
Publicado: (2023)

Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity
por: Atretkhany, Kamar-Sulu N., et al.
Publicado: (2018)

Regulation of Intrinsic and Bystander T Follicular Helper Cell Differentiation and Autoimmunity by Tsc1
por: Zhang, Shimeng, et al.
Publicado: (2021)

WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity
por: Becker-Herman, Shirly, et al.
Publicado: (2011)

An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders
por: Alghamdi, Mohammed, et al.
Publicado: (2019)

Intrinsic autoimmune capacities of hematopoietic cells from female New Zealand hybrid mice
por: David, Alexandria, et al.
Publicado: (2014)

Schmallenberg virus induces apoptosis in Vero cell line via extrinsic and intrinsic pathways in a time and dose dependent manner
por: AKSOY, Emel, et al.
Publicado: (2018)

Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity
por: Kaminski, Amber, et al.
Publicado: (2018)

PI3K Orchestrates T Follicular Helper Cell Differentiation in a Context Dependent Manner: Implications for Autoimmunity
por: Preite, Silvia, et al.
Publicado: (2019)

An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity
Publicado: (1991)

A T cell-intrinsic function for NF-κB RelB in experimental autoimmune encephalomyelitis
por: Lalle, Guilhem, et al.
Publicado: (2021)

Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses
por: Li, Yanchuan, et al.
Publicado: (2016)

Familial hemophagocytic lymphohistiocytosis hepatitis is mediated by IFN-γ in a predominantly hepatic-intrinsic manner
por: Diamond, Tamir, et al.
Publicado: (2022)

Training certified detectives to track down the intrinsic shortcuts in COVID-19 chest x-ray data sets
por: Zhang, Ran, et al.
Publicado: (2023)

Training certified detectives to track down the intrinsic shortcuts in COVID-19 chest x-ray data sets
por: Zhang, Ran, et al.
Publicado: (2023)

Molecular mechanism for impaired suppressive function of Tregs in autoimmune diseases: A summary of cell‐intrinsic and cell‐extrinsic factors
por: Yang, Luting, et al.
Publicado: (2020)

Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice
por: Chin, Shu Shien, et al.
Publicado: (2013)

Multimodal analgesia for treatment of allodynia and hyperalgesia after major trauma in a cat
por: Goich, Mariela, et al.
Publicado: (2019)

Dendritic cells efficiently transmit HIV to T Cells in a tenofovir and raltegravir insensitive manner
por: Kim, Jocelyn T., et al.
Publicado: (2018)

Notch Signaling in B Cell Immune Responses
por: Garis, Matthew, et al.
Publicado: (2021)

B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6
por: Jackson, Shaun W., et al.
Publicado: (2016)

Complement Component C4 Regulates the Development of Experimental Autoimmune Uveitis through a T Cell-Intrinsic Mechanism
por: Zhang, Lingjun, et al.
Publicado: (2017)

Dual inhibition of DNMTs and EZH2 can overcome both intrinsic and acquired resistance of myeloma cells to IMiDs in a cereblon‐independent manner
por: Dimopoulos, Konstantinos, et al.
Publicado: (2017)

Cortical Signatures of Dyslexia and Remediation: An Intrinsic Functional Connectivity Approach
por: Koyama, Maki S., et al.
Publicado: (2013)

Transcriptional Repressor Domain of MBD1 is Intrinsically Disordered and Interacts with its Binding Partners in a Selective Manner
por: Hameed, Umar Farook Shahul, et al.
Publicado: (2014)

Interleukin-6 Derived from the Central Nervous System May Influence the Pathogenesis of Experimental Autoimmune Encephalomyelitis in a Cell-Dependent Manner
por: Sanchis, Paula, et al.
Publicado: (2020)

Tregs in Autoimmunity: Insights Into Intrinsic Brake Mechanism Driving Pathogenesis and Immune Homeostasis
por: Bednar, Kyle J., et al.
Publicado: (2022)

Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner
por: Long, Yiru, et al.
Publicado: (2023)

Targeting B Cells and Plasma Cells in Autoimmune Diseases
por: Hofmann, Katharina, et al.
Publicado: (2018)

Alzheimer's Disease: A Pathogenetic Autoimmune Disorder Caused by Herpes Simplex in a Gene-Dependent Manner
por: Carter, C. J.
Publicado: (2010)

Cell Fusion along the Anterior-Posterior Neuroaxis in Mice with Experimental Autoimmune Encephalomyelitis
por: Sankavaram, Sreenivasa R., et al.
Publicado: (2015)

Manners
Publicado: (1863)

Cannot write session to /tmp/vufind_sessions/sess_mn06i91vbguor79aig06t8u2kg